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Cervical cancer and HPV infection

Time: 2013-07-02 21 : 52Source : Internet
Relationship between HPV infection and cervical cancer and its detection
Cervical cancer is currently the second most malignant tumor that threatens women's health, and HPV infection is closely related to cervical cancer.
HPV is a group of viruses collectively called human papilloma. It can be divided into many subtypes clinically, and different subtypes can cause different diseases. Whether HPV-positive women can progress to high levels of cervical intraepithelial lesions and cancer is strongly related to the type of HPV.
According to different types of HPV and tumor risk, HPV is divided into low-risk type and high-risk type. Low-risk types of HPV include HPV 6, 11, 42, 43, 44, and other benign lesions such as genital warts, including low-grade cervical intraepithelial lesions (CIN I). High-risk HPV includes HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68 and other types of HPV, and those with cervical cancer and cervical intraepithelial lesions (CIN II / III) Related, especially HPV16 and 18 types.
Whether HPV-positive women can progress to high levels of cervical intraepithelial lesions and cancers is not only related to the type of HPV infection, but also related to the HPV DNA dose level and the time of first HPV infection.
According to long-term observations by medical experts, HPV can be detected in 99.8% of patients with cervical cancer, while HPV-negative patients rarely develop cervical cancer. In addition, more than 98% of patients with cervical disease also have HPV. During the long incubation period, any gynecological examination and cancer screening can detect the precancerous lesions of the cervix. Through HPV screening, we can know exactly how we may be affected, so that we can detect and treat early. It takes about 10 years from the occurrence of HPV lesions to the development of cervical cancer. Early detection and early treatment during this period can effectively avoid the occurrence of cervical cancer.
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